All research involving recombinant DNA^* must comply with federal regulations and guidelines and must be registered with the University (this applies to Campus Schools^*, Schools of Medicine and Nursing, and Health System investigators). Registration forms must be completed and submitted to the Biological Safety Division of the Occupational and Environmental Safety Office (OESO^*) for review and approval by the Institutional Biosafety Committee(IBC^*) in accordance with NIH^* rDNA^* Guidelines.

If the research involves viral vectors, there is a separate viral vector registration form that must be completed and submitted to the Biological Safety Division for IBC^* review and approval. If viral vector work is to be conducted in animals, a Standard Operating Procedure for safe handling of animals must also be submitted for IBC^* review and approval.

Experiments involving the deliberate transfer of rDNA^* into human subjects must also be reviewed and approved by the IBC^*, IRB^*, and the NIH^* Office of Biotechnology Activities. The Clinical Research Pharmacy and Infection Control must also approve the clinical procedures when a biological vector is used in a clinical trial.